Impact of liver resection on portal venous pressure and renal function

Liver dysfunction - in correlation to the severity of functional impairment - but also any increase in portal pressure per se (hepatorenal reflex) can induce alterations in renal function and ultimately result in hepatorenal syndrome (HRS). In this prospective investigation we determined the impact of liver resection on portal venous pressure by measuring the hepatic venous pressure gradient (HVPG), on concentrations of vasoactive peptides and on renal function.