Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: A report of four patients

Ph-like acute lymphoblasticleukemia ( Ph-like ALL) represents a high-risk subgroup of B-cell ALL.[1][1]–[7][2] By gene-expression, these patients have a profile similar to that of Ph+ ALL; however, they lack the BCR-ABL1 fusion. Patients with Ph-like ALLharbor a diverse range of genetic