Considerations on designs of intranasal studies for abuse-deterrent products

sensitivity (ˇC =−0.74, p<0.01; ˇO =−0.28, p<0.01), and income sensitivity (ˇC =0.66, p<0.01; ˇO =0.46, p<0.01). The evidence of interactions between the price of one drug and the consumption of another drug are, however, mixed, and drug-specific. Conclusions: The behavior of populations that simultaneously consume cannabis and opium suggests that consumers treat them as substitutes or complements for each other. A key implication of this finding is that the control of one drug may simply lead to consumers switching to or reducing the consumption of the other drug. Financial Support: This research benefited from funding from the NIH under NIDA grants 1R21 DA025917 and 1R21 DA020160.