Heritability in genetic heart disease: the role of genetic background

Joeri A. Jansweijer,Karin Y. van Spaendonck-Zwarts,Michael W. T. Tanck,J. Peter van Tintelen,Imke Christiaans,Jasper J. van der Smagt,Alexa M.C. Vermeer,J. Martijn Bos,Arthur J. Moss,Heikki Swan,S. G. Priori,Annika Rydberg,Jacob Tfelt-Hansen,Michael J. Ackerman,Iacopo Olivotto,Philippe Charron,Juan R. Gimeno,Maarten P. van den Berg,Arthur Am Wilde,Yigal M. Pinto

Heritability in genetic heart disease: the role of genetic background

2019

Background: Mutations in genes encoding ion channels or sarcomeric proteins are an important cause of hereditary cardiac disease. However, the severity of the resultant disease varies considerably ...

Keywords:

Channelopathy
Heritability
Genetics
Disease
Hypertrophic cardiomyopathy
Twin study
Biology
Medical genetics
idiopathic dilated cardiomyopathy
Heart disease

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