Absence of significant hemodynamic changes in the fetus following maternal betamethasone administration
1996
Maternal
betamethasoneadministration causes a transient but considerable reduction in fetal body and breathing movements and in fetal heart rate variation. The aim of the present prospective study was to investigate whether there is evidence of circulatory changes in fetal, placental or
uterine arteries, consistent with
hypoxemia. Eighteen women at risk for preterm delivery received
betamethasoneto enhance fetal lung maturation.
Doppler studieswere performed before treatment, and 24 and 72 h after the second dose of
betamethasone. Blood flow velocity waveforms were obtained from both
uterine arteries,
umbilical arteries, fetal
descending aorta, fetal renal artery, and fetal cerebral arteries. No significant changes occurred in the
pulsatility indexof any of these blood vessels, suggesting that the transient reduction in fetal heart rate variation and fetal body and maternal
betamethasonethrough fetal bypoxemia. Copyright © 1996 International Society of Ultrasound in Obstetrics and Gynecology
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