Dramatic effects of eculizumab in a child with diffuse proliferative lupus nephritis resistant to conventional therapy
2015
Background Treatment of
systemic lupus erythematosus(SLE) with severe
diffuse proliferative nephritisis often challenging, particularly in small children in whom a genetic conditioning is likely to play a role. The effectiveness of standard therapy based on glucocorticoid and
immunosuppressive drugsis often unsatisfactory.
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