Response to Commentary on "Grey Matter Abnormalities in First Episode Mania: A Systematic Review and Meta-analysis of Voxel-Based Morphometry Studies".

We appreciate the comments by Sheng and colleagues1 on our manuscript titled "Grey matter abnormalities in first-episode mania: A systematic review and meta-analysis of voxel-based morphometry studies 2 " and would like to take this opportunity to clarify our methodology and share the findings of additional analyses we have performed.