ESD for Colon

Endoscopic submucosal dissection (ESD) technique, originally developed in Japan, allows en bloc resection of early colorectal tumors in any size. Endoscopic mucosal resection (EMR) had been the only treatment available for large colorectal neoplasms before ESD technique has been launched. However, en bloc resection rate of EMR for lesions greater than 20 mm was unsatisfactory, leading to high proportion of local recurrence. Given that ESD has been confirmed to be superior to EMR with a significantly higher rate of en bloc resection (ESD 84%, EMR 33%) [1] and lower local recurrence rate (ESD1.4%, EMR 6.8%) [2], it is becoming the standard treatment for laterally spreading tumors.