S‐(3‐Hydroxypropyl)mercapturic acid (HPMA) [Biomonitoring Methods, 2010]

Published in the series Biomonitoring Methods, Vol. 12 (2010) The article contains sections titled: General principles Equipment, chemicals and solutions Equipment Chemicals Solutions Calibration standards Specimen collection and sample preparation Sample preparation Operational parameters Operational parameters for high performance liquid chromatography Operational parameters for mass spectrometry Analytical determination Calibration Calculation of the analytical result Standardisation and quality control Evaluation of the method Precision Accuracy Detection limit and quantification limit Sources of error Discussion of the method Keywords: determination in urine; high performance liquid chromatography; tandem mass spectrometric detection; LC/MS/MS; analysis in biological materials; occupational monitoring; analytical method; biomarker; metabolites