Mitral Valve Replacement in Idiopathic Eosinophilic Endocarditis Without Peripheral Eosinophilia

Abstract Idiopathic hypereosinophilic syndrome(IHS) is a rare systemic diseasethan can cause multiple organ failure by eosinophilicinfiltration. Cardiac involvement is characterized by endocardial fibrosisand overlying thrombus leading to restrictive cardiomyopathyand valvular dysfunction. The absence of peripheral eosinophiliadoes not exclude eosinophiliccardiac involvement. Surgical experience of patients with mitral dysfunction caused by this syndrome is limited and valvular replacement is most often performed. Mechanical valvular replacement has a high incidence of recurrent obstructive thrombosis and replacement by bioprosthesis is recommended despite associated restrictive cardiomyopathy. This report describes a patient who presented mitral insufficiency caused by eosinophilicendocarditis without peripheral eosinophiliawho underwent mitral valve replacement.