THE BEA SCORE IN CHRONIC HEPATITIS B AND DELTA

Purpose: To study the BEA score ( Baseline Event-anticipation score ) and its correlation with biological signs of liver laboratory syndromes in the patients with chronic hepatitis B and Delta. Material and method . There were investigated prospectively 58 Caucasian patients with chronic hepatitis B and Delta (CHD), 28 women and 30 men, and 10 Caucasian patients with viral liver cirrhosis Delta (LCD). BEA score was estimated using the online calculator ( http://hepatitis-delta.org/physicians-and-scientists/calculators/ ). There was estimated the BEA score and the indicators of the biological liver syndromes were studied. The correlation analysis was performed (after Spearman ) between the score values of BEA parameters and the biological liver syndromes. Results: It was established the direct correlation of the BEA score with the values of the levels of serum gamma-glutamyl transferees and with the serum total bilirubin in patients with HCD. In patients with LCD there was determined direct correlation of the BEA score with the total bilirubin and inverse correlation with the serum albumin values. Conclusions: We recommend modifying the BEA score by adding the albumin and GGT as predictors for developing complications related to liver disease.