Analysis of Cerebrospinal Fluid Soluble TREM2 and Polymorphisms in Sporadic Parkinson’s Disease in a Chinese Population

Background Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial surface receptor that mediates the degradation disorder of amyloid β (Aβ) in Alzheimer’s disease. However, the role of TREM2 in Parkinson’s disease (PD) and α-Synclein (α-Syn) degradation is largely unknown.