DNA methylation–based immune response signature improves patient diagnosis in multiple cancers
2017
The tumor immune response is increasingly associated with better clinical outcomes in breast and other cancers. However, the evaluation of tumor-infiltrating lymphocytes (TILs) relies on histopathological measurements with limited accuracy and reproducibility. Here, we profiled DNA methylation markers to identify a methylation of TIL (MeTIL) signature that recapitulates TIL evaluations and their prognostic value for long-term outcomes in breast cancer (BC).
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
52
References
55
Citations
NaN
KQI