COMPARISON OF DIGITAL 12-LEAD ECG AND DIGITAL 12-LEAD HOLTER ECG RECORDINGS IN HEALTHY MALE SUBJECTS

Background: Numerous publications on Thorough QT (TQT) studies display a wide range in ECG variability. Our meta-analysis study investigating the effects of (a) the baseline correction method (b) the design (c) the ECG recording method demonstrated that only the ECG recording method had a significant impact on data variability and it appears that digitally recorded 12-lead bedside ECG are superior when compared to digital 12-lead Holter ECG recordings (Naseem et al, 2009).