Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity
2017
To the editor: Sezary syndrome (SS) is a rare, aggressive leukemic form of primary
cutaneous T-cell lymphoma.[1][1] The diagnostic criteria associate a clonal
T-cell receptor(TCR) rearrangement with peripheral Sezary cell (SC) counts of ≥1 G/L, an increased CD4/CD8 ratio of ≥10, CD4+CD7−
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