Selective Formation of Porous Pt Nanorods for Highly Electrochemically Efficient Neural Electrode Interfaces

The enhanced electrochemical activity of nanostructured materials is readily exploited in energy devices, but their utility in scalable and human-compatible implantable neural interfaces can significantly advance the performance of clinical and research electrodes. We utilize low-temperature selective dealloying to develop scalable and biocompatibleone-dimensional platinum nanorod (PtNR) arrays that exhibit superb electrochemical properties at various length scales, stability, and biocompatibilityfor high performance neurotechnologies. PtNR arrays record brain activity with cellular resolution from the cortical surfaces in birds and nonhuman primates. Significantly, strong modulation of surface recorded single unit activity by auditory stimuli is demonstrated in European Starlingbirds as well as the modulation of local field potentialsin the visual cortexby light stimuli in a nonhuman primateand responses to electrical stimulation in mice. PtNRs record behaviorally and physiologically relevant neuro...