Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis.

ABSTRACTSevere acute pancreatitisremains a life-threatening disease with a high mortality rate among a defined proportion of those affected. Apoptosis has been hypothesized to be a beneficial form of cell death in acute pancreatitis. Honokiol, a low-molecular-weight natural product, possesses the a