Risk of Hematologic Events With Coadministration of Methotrexate and the Breast Cancer Resistance Protein Inhibitor Febuxostat.

Satoru Mitsuboshi,Takahiro Niimura,Masaya Kanda,Shunsuke Ishida,Yoshito Zamami,Keisuke Ishizawa

Risk of Hematologic Events With Coadministration of Methotrexate and the Breast Cancer Resistance Protein Inhibitor Febuxostat.

2021

Satoru Mitsuboshi
Takahiro Niimura
Masaya Kanda
Shunsuke Ishida
Yoshito Zamami
Keisuke Ishizawa

Background:The breast cancer resistance protein (BCRP) is a key drug transporter found in the liver, kidney, central nervous system, and gastrointestinal tract. Due to the wide expression of BCRP, ...

Keywords:

Febuxostat
Medicine
Kidney
Pharmacology
Allopurinol
drug transporter
Methotrexate
Central nervous system
Abcg2
Gastrointestinal tract

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