FIXATION OF RAT TAIL VERTEBRAE CAUSES MUSCLE FIBRE TYPE TRANSITION IN PARASPINAL MUSCLE
2018
Summary StatementParaspinal
musclecontain higher
proportionof slow-twich fibers. The fixation of the rat tail induced transition of
musclefiber
typesin the paravertebral
musclescharacterised by the decrease in the
proportionof the slow
typemyosin heavy chain.IntroductionLumbar degenerative
kyphosisoften accompanies back pain, easy fatigability, fatty degeneration and atrophy of
back muscles. There are two
typesof skeletal
musclefibers according to oxidative activities: slow-twich (
Type1) and fast-twitch (
Type2) fibers.
Type2 fibers were subdivided into three
types:
Type2A, 2B and 2D/X. Each fiber
typeprimarily expresses a specific isoform of myosin heavy chain (MHC). It has been known that
back musclescontain higher
proportionof MHC
type1. However, the impact of
kyphosison the
proportionof fiber
typesin the paravertebral
muscleshas not been fully understood. The aim of this study is to analyze the transition of
musclefiber
typesafter kyophotic or straight fixation using a rat tail ...
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