An Assessment of the Concentration-Related Prognostic Value of Cardiac Troponin I Following Acute Coronary Syndrome

In 2004 the British Cardiac Society redefined myocardial infarction by cardiac troponin I(cTnI) concentration: ≤0.06 μg/L ( unstable angina), >0.06 to 0.06- to 80 years (3.30, 3.50 to 5.06), peripheral vascular disease (1.50, 1.16 to 1.94), heart failure (1.36, 1.05 to 1.83), diabetes mellitus (1.68, 1.36 to 2.07), severe left ventricular systolic dysfunction (1.50, 1.00 to 2.21), and creatinine per 10 μmol/L (1.65, 1.02 to 1.08), whereas ages 50 to 60 years (0.55, 0.32 to 0.96), β blockers (0.53, 0.44 to 0.64), aspirin (0.80 0.65 to 0.99), angiotensin-converting enzyme inhibitors(0.67, 0.56 to 0.80), statins (0.73, 0.59 to 0.90), and revascularization (0.33, 0.12 to 0.92) were associated with a lower riskof death. In conclusion, although quantitative evaluation of cTnI concentration in patients with acute coronary syndromewith cTnI >0.06 μg/L was associated with no added prognostic information, the dichotomization of patients by cTnI status (“positive” and “negative”) facilitates acute coronary syndromerisk stratification.