Clinical Validation of a Blood-Based Predictive Test for Stratification of Response to Tumor Necrosis Factor Inhibitor Therapies in Rheumatoid Arthritis Patients

Theodore Mellors,Johanna B. Withers,Asher Ameli,Alex Jones,Mengran Wang,Lixia Zhang,Helia N. Sanchez,Marc Santolini,Italo Faria do Valle,Michael Sebek,Feixiong Cheng,Dimitrios A. Pappas,Joel M. Kremer,Jeffery R. Curtis,Keith J. Johnson,Alif Saleh,Susan D. Ghiassian,Viatcheslav R. Akmaev

Clinical Validation of a Blood-Based Predictive Test for Stratification of Response to Tumor Necrosis Factor Inhibitor Therapies in Rheumatoid Arthritis Patients

2020

Theodore Mellors
Johanna B. Withers
Asher Ameli
Alex Jones
Mengran Wang
Lixia Zhang
Helia N. Sanchez
Marc Santolini
Italo Faria do Valle
Michael Sebek
Feixiong Cheng
Dimitrios A. Pappas
Joel M. Kremer
Jeffery R. Curtis
Keith J. Johnson
Alif Saleh
Susan D. Ghiassian
Viatcheslav R. Akmaev

Objectives: For rheumatoid arthritis (RA) patients failing to achieve treatment targets with conventional synthetic disease-modifying antirheumatic drugs, tumor necrosis factor (TNF)-α inhibitors (...

Keywords:

Rheumatoid arthritis
Internal medicine
Tumor necrosis factor alpha
Predictive testing
Oncology
Medicine

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