Phase analysis of the cardiac cycle in patients with arterial hypertension based on the results of equilibrium radioventriculography

AIM: To study cardiac cycle parameters in patients with grade I and II AH by equilibrium radioventriculography (ERVG) and the possibility of using them for diagnostics of systolic and diastolic myocardial dysfunction. MATERIALS AND METHODS: Left and right ventricular diastolic and systolic functions were evaluated by conventional ERVG using a MB-9100 gamma-chamber (Gamma, Hungary) and the Gold-Rada+ system for data collection and processing. The study involved 142 patients divided into 3 groups. Group 1 included 38 patient with grade 1 AH (mean age 20.7 +/- 6.2 yr), group 2 85 patients with grade II AH (58.7 +/- 10.7 yr), group 3 19 practically healthy subjects (29.4 +/- 10.8 yr). RESULTS: No significant abnormalities in hemodynamic characteristics except increased filling of the right ventricle for 1/3 diastole were observed in group 1. Decreased filling for 1/3 diastole, maximum filling rate, and the ratio of filling to ejection rates were revealed in group 2. In order to counterbalance HR differences, the time-related ERVG values were calculated per RR interval; it allowed to reveal diastolic disorders confirmed in the study of ERVG "hemodynamics characteristics. Patients with grade II AH showed a longer time of maximum filling rate with respect to left and right ventricular RR intervals compared with controls. In group 1, this parameter was lower than in healthy subjects.