Abstract 14148: Local Aldosterone Production via StAR in PAH and in Human IPS Cell-derived Cardiomyocytes: Efficacy of Spironolactone in Cardiac Remodeling and Mitochondrial Dynamics Under Hypoxic Stress

Objective: Pulmonary arterial hypertension (PAH) is a progressive disease that frequently leads to right ventricular (RV) remodeling. Increased plasma aldosterone levels have been reported in patie...