Tuberculosis treatment outcomes among people living with HIV diagnosed using Xpert MTB/RIF versus sputum-smear microscopy in Botswana: a stepped-wedge cluster randomised trial

Tefera Agizew,Violet N. Chihota,Sambayawo Nyirenda,Zegabriel Tedla,Andrew F. Auld,Unami Mathebula,Anikie Mathoma,Rosanna Boyd,Anand Date,Sherri L. Pals,Phenyo Lekone,Alyssa Finlay

Tuberculosis treatment outcomes among people living with HIV diagnosed using Xpert MTB/RIF versus sputum-smear microscopy in Botswana: a stepped-wedge cluster randomised trial

2019

Tefera Agizew
Violet N. Chihota
Sambayawo Nyirenda
Zegabriel Tedla
Andrew F. Auld
Unami Mathebula
Anikie Mathoma
Rosanna Boyd
Anand Date
Sherri L. Pals
Phenyo Lekone
Alyssa Finlay

Background Xpert® MTB/RIF (Xpert) has high sensitivity for diagnosing tuberculosis (TB) compared to sputum-smear microscopy (smear) and can reduce time-to-diagnosis, time-to-treatment and potentially unfavorable patient-level treatment outcome.

Keywords:

Medical microbiology
Virology
Medicine
Tuberculosis
smear microscopy
Tropical medicine
Internal medicine
Parasitology
Odds ratio
Rate ratio
Pathology
Hazard ratio
Confidence interval
treatment outcome
Interquartile range
GeneXpert MTB/RIF

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