Labeling Monoclonal Antibody with α-emitting 211At at High Activity Levels via a Tin Precursor.

Ganesan Vaidyanathan,Oscar R. Pozzi,Jaeyeon Choi,Xiao-Guang Zhao,Shawn P. Murphy,Michael R. Zalutsky

Labeling Monoclonal Antibody with α-emitting 211At at High Activity Levels via a Tin Precursor.

2020

Ganesan Vaidyanathan
Oscar R. Pozzi
Jaeyeon Choi
Xiao-Guang Zhao
Shawn P. Murphy
Michael R. Zalutsky

Background: In a previous clinical study, the authors evaluated the potential of antitenascin C monoclonal antibody (mAb) 81C6 labeled with 211At via the prosthetic agent N-succinimidyl 3-[211At]as...

Keywords:

Radioimmunotherapy
Monoclonal antibody
clinical study
Tin
Molecular biology
Targeted Radiotherapy
Medicine
high activity
α particles

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