Selective and comprehensive analysis of organohalogen compounds by GC × GC–HRTofMS and MS/MS
2018
Thousands of organohalogen compounds, including hazardous chemicals such as polychlorinated biphenyls (PCBs) and other
persistent organic pollutants(POPs), were selectively and simultaneously detected and identified with simple, or no, purification from environmental sample extracts by using several advanced methods. The methods used were software extraction from
two-dimensional gaschromatography–high-resolution time-of-flight mass spectrometry (GC × GC–HRTofMS) data, measurement by negative
chemical ionizationwith HRTofMS, and neutral loss scanning (NLS) with GC × GC–MS/MS. Global and selective detection of organochlorines and bromines in environmental samples such as sediments and fly ash was achieved by NLS using GC × GC–MS/MS (QQQ), with the
expected lossesof 35Cl and 79Br. We confirmed that negative
chemical ionizationwas effective for sensitive and selective ionization of organohalogens, even using GC × GC–HRTofMS. The 2D total ion chromatograms obtained by using negative
chemical ionizationand selective extraction of organohalogens using original software from data measured by electron
impact ionizationwere very similar; the software thus functioned well to extract organohalogens. Combining measurements made by using these different methods will help to detect organohalogens selectively and globally. However, to compare the data obtained by individual measurements, the retention times of the peaks on the 2D chromatograms need to match.
Keywords:
-
Correction
-
Source
-
Cite
-
Save
28
References
12
Citations
NaN
KQI