Derivatives of 6- (6-substituted-triazolopyridazine-sulfanyl) 5-fluoro-benzothiazole and 5-fluoro-benzimidazoles: preparation, use as medicines and use as inhibitors of met.

The invention concerns novel products of formula (I): wherein represents a single or double bond; F represents a fluorine atom, Ra is H, Hal, alkoxy, O-cycloalkyl, heteroaryl, phenyl, NHCOalk, NHCOcycloalk or NR1R2; X represents S, SO or SO; A is NH or S; W represents H, alkyl or COR where R is cycloalkyl; alkyl optionally substituted with NR3R4, alkoxy, hydroxy, phenyl, heteroaryl, or heterocycloalkyl; alkoxy optionally substituted with NR3R4, ie a radical O- (CH2) n-NR3R4, O-phenyl or O- (CH2) n-phenyl, optionally substituted with phenyl and n = 1 to 4; or the group NR1 R2; R1 represents H or alk and R2 is H, cycloalkyl or alkyl; R3 and R4 are H, Alk, cycloalkyl, heteroaryl or phenyl; R1, R2 and / or R3, R4 together with N form a ring optionally containing O, S, N and / or NH; all heterocycloalkyl, heteroaryl and phenyl and ring being optionally substituted; these products being in all isomeric forms and salts, as medicaments, in particular as MET inhibitors.