Badania własne nad etiologią zakażeń układu moczowego u dzieci z zaburzeniami anatomicznymi i czynnościowymi dróg moczowych

Background. Urinary tract infection (UTI) is one of the most common bacterial infection in children. Anatomic and functional abnormalities of urinary tract increase the incidence of UTI. Knowledge about current etiological factors of UTI in children with urinary tract abnormalities enables to select the appropriate empiric therapy. Objectives. The occurrence of pathogens causing UTI in children with anatomic and func­tional abnormalities of urinary tract was analyzed. Material and methods. Medical records of children with UTI hospitalized in the Department of Pediatric Nephrology, Medical University of Lublin in 2009–2013 were studied. The patients were divided into four groups: A — with vesicoureteral reflux, B — with other anatomic abnormalities of urinary tract, C — with neurogenic bladder dysfunction and D — with non-neurogenic bladder dysfunctions. Results. In all children, Escherichia coli was the most common invading pathogen. Klebsiella spp . occured significantly more commonly in group A as compared to groups A and C. Pseudomonas aeruginosa was cultured significantly more commonly in group C in comparison with groups B and D. In group A, Escherichia coli and Enterococcus spp . were observed significantly more commonly in girls than in boys. Similarly, in group C and group D, Escherichia coli was cultured significantly more commonly in girls than in boys. Conclusions. 1. In all children, Escherichia coli was the most common invading pathogen. 2. In children with vesicoureteral reflux, Klebsiella spp . was cultured more commonly than in those with other abnormalities. 3. In children with neurogenic bladder, infections with Pseudomonas aeruginosa occurred more commonly than in those with other abnormalities.